Resources at Oak Crest

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The facilities at Oak Crest Institute of Science are housed in a building of approximately 10,000 ft2, and are arranged in an open-planning design as well as dedicated laboratories. The following infrastructure is available to researchers.

  • Atmospheric Chemistry and Aerosol Research Laboratory.The atmospheric chemistry and aerosol research facility houses equipment and instrumentation for the generation and measurement of gas-phase and aerosol standards in the laboratory, and for the collection and analysis of environmental gas and aerosol samples in the field.
  • Biomedical R&D Facilities. The biomedical laboratory is housed in a dedicated facility and includes a pilot-scale manufacturing space as well as a hard-wall class 10,000 clean room.
  • Chromatography. Oak Crest’s chromatography laboratory provides a wide array of liquid and gas chromatographic techniques including HPLC and LC-MS, ion chromatography, and GC and GC-MS.
  • Electrochemistry. Electrochemical measurements including cyclic and linear-sweep voltammetry are carried out using both digital and analog potentiostats. Modular instrumentation and software written in-house allows for both routine use of standard electrochemical techniques and the rapid development of new methods.
  • Imaging Core. The Imaging Core is a resource for microscopy applications, specialized preparation techniques, immunolabeling, and the expertise to guide and troubleshoot biomedical and environmental research projects to seamlessly integrate imaging data.
  • Instrumentation Development Facility. Oak Crest’s instrumentation facility allows development of novel instruments for laboratory and field-based spectroscopic measurements, medical devices, and other custom laboratory equipment and instrumentation. The facility includes an electronics design and assembly laboratory and a fully-equipped machine shop for mechanical fabrication.
  • Laser Laboratory. The laser spectroscopy laboratory provides facilities for laser-based ground and excited-state spectroscopic techniques.
  • Microbiology Laboratory. The dedicated microbiology laboratory provides facilities for sample preparation, growth and isolation, including a separate anaerobic culture laboratory.
  • Molecular Biology LaboratoryThe molecular biology laboratory is housed in a dedicated facility and includes equipment and instrumentation for DNA and RNA isolation and purification. Separate, dedicated laboratories include facilities for proteomics and metagenomics, as well as a high-throughput sample processing facility.
  • Spectroscopy. A broad array of spectroscopic techniques are available at Oak Crest, including UV-visible and infrared absorption spectroscopy, fluorescence spectroscopy, Raman spectroscopy, and multi-nuclear NMR spectroscopy.
  • Tissue Culture Laboratories. Two tissue culture facilities are available at Oak Crest, each supplied with HEPA-filtered air, one for sterile culture and another BSL-2 facility where bacteria and viruses can be studied alongside human cell lines.
  • Wet and Synthetic Chemistry Laboratories. Facilities for synthetic chemistry are located in a large, open=planning wet-lab space that is fully-equipped for carrying out traditional bench-top chemical synthesis, vacuum-lines and glove-box based inert atmosphere chemistry, and gas-phase chemical reactions.